Heterocyclic and heteroaryl thereof, ILO

摘要

Compounds are described that adhere to vla-4.Some of these compounds also inhibit leukocyte adhesion and a particularThe deleucocitos vla-4 adhesion of intermediate compounds useful for the treatment of diseases in a Mammalian Patient atorias flammable, for example in a Human, such as Asthma,Alzheimer's disease, ateroes - clerosis caused by AIDS, dementia, diabetes, inflammatory bowel disease, artritisreumatoide, tissue transplantation,Metu00e1stas is tumors and Myocardial Ischemia. The compounds can also be provided for the treatment of inflammatory Brain diseases such as multiple sclerosis.