首页> 外国专利> Use of a non-laboratory virus strain, methods for determining whether a gene has an effect on a phenotype associated with a peripheral and central nervous system disorder or on a peripheral and central nervous system cell to determine whether a gene encodes an antigen associated with a pathogenic infection or cancer, to determine the suitability of a non-laboratory virus strain for modification to a modified strain, to determine whether a gene enhances the anti-tumor effects of a virus, and to produce an oncolytic non-laboratory virus strain. , modified, non-laboratory virus strain, use of a gene, hsv1 js1 strain, pharmaceutical composition, and, methods for treating a tumor in an individual, supplying a gene to an individual and treating or preventing a disorder of the peripheral nervous systems and central

Use of a non-laboratory virus strain, methods for determining whether a gene has an effect on a phenotype associated with a peripheral and central nervous system disorder or on a peripheral and central nervous system cell to determine whether a gene encodes an antigen associated with a pathogenic infection or cancer, to determine the suitability of a non-laboratory virus strain for modification to a modified strain, to determine whether a gene enhances the anti-tumor effects of a virus, and to produce an oncolytic non-laboratory virus strain. , modified, non-laboratory virus strain, use of a gene, hsv1 js1 strain, pharmaceutical composition, and, methods for treating a tumor in an individual, supplying a gene to an individual and treating or preventing a disorder of the peripheral nervous systems and central

机译:使用非实验室病毒株,确定基因是否对与周围和中枢神经系统疾病有关的表型或对周围和中枢神经系统细胞有影响的方法,以确定基因是否编码与肝炎相关的抗原致病性感染或癌症,以确定非实验室病毒株对修饰菌株的适应性,确定基因是否增强病毒的抗肿瘤作用,并产生溶瘤性非实验室病毒株。 ,修饰的非实验室病毒株,基因的用途,hsv1 js1株,药物组合物以及治疗个体肿瘤,向个体提供基因并治疗或预防周围神经系统疾病的方法中央

摘要

"USE OF A NON-LABORATORY VIRUS CUP METHOD FOR DETERMINING IF A GENE HAS AN EFFECT ON A PHENOTYPLE ASSOCIATED WITH A PERIPHERAL AND CENTRAL NERVOUS SYSTEMS FOR A CELL OF THE NUMEROUS PERIPHERAL CINEMARIAN SYSTEMS ASSOCIATED WITH A PATHOGENIC INFECTION OR CANCER TO DETERMINE THE SUITABILITY OF A NON-LABORATORY VIRUS CUP FOR MODIFICATION TO A MODIFIED CUP TO DETERMINE IF A GENE INCREASES ANTI-TUMOR EFFECTS OF A VIRAL VIRAL NURPLE , MODIFIED, NON-LABORATORY VIRUS CUP, USE OF A GENE, CEPA HSV1 JS1, PHARMACEUTICAL COMPOSITION, AND, METHODS TO TREAT A TUMOR IN AN INDIVIDUAL AND TO TREAT A DIFFERENT OR IMPIRES DURING THE PERSPECTIVE AND CENTRAL ". The present invention relates to non-laboratory virus strains, for example of herpes viruses, such as HSV, with improved oncolytic and / or genetic supply capabilities compared to laboratory virus strains.
机译:“使用非实验室病毒杯法测定基因是否对与致癌性或致癌性相关的许多外周电影系统的细胞与周围和中枢神经系统相关的表型有影响一种非实验室病毒杯,用于修改基因后的修饰杯,以确定基因是否会增加病毒性病毒的抗肿瘤作用,修饰的,非实验室病毒杯,基因的使用,CEPA HSV1 JS1,PHOS,药物在个体和中枢治疗个体肿瘤并治疗不同或有害的方法。本发明涉及与实验室病毒株相比具有改善的溶瘤和/或遗传供应能力的非实验室病毒株,例如疱疹病毒,例如HSV。

著录项

  • 公开/公告号BR0107736A

    专利类型

  • 公开/公告日2002-11-19

    原文格式PDF

  • 申请/专利权人 BIOVEX LIMITED;

    申请/专利号BR20010107736

  • 发明设计人 ROBERT STUART COFFIN;

    申请日2001-01-22

  • 分类号C12N15/869;C12N7/01;A61K48/00;C12Q1/02;

  • 国家 BR

  • 入库时间 2022-08-22 00:03:51

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