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Method for immunomodulation by adoptive transfer of antigen-specific cytotoxic T cells
Method for immunomodulation by adoptive transfer of antigen-specific cytotoxic T cells
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机译:通过抗原特异性细胞毒性T细胞的过继转移进行免疫调节的方法
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摘要
A method for the production of antigen-specific cytotoxic T-cells (CTLs) by incubating a T cell-containing cell preparation with said antigen and isolating said antigen-specific CTLs, characterized by i) activating proliferation of CTLs in the cell preparation by incubation with the antigen; ii) selectively transferring a vector into the proliferating CTLs, said vector containing a marker gene by means of which marked and non-marked cells can be separated; and iii) separating the transfected antigen-specific CTLs on the basis of said marker gene, is useful for immunomodulation.
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