NOVEL INTERMEDIATE COMPOUNDS AS THEIR APPLICATION IN PRODUCTION OF BISINDOLILOAMALEIMIDES WITH A N,N'-BRIDGE

摘要

This invention provides compounds of the formula: CHEM The invention further provides the use of this compound to prepare N,N'-bridged bisindolylmaleimides. Furthermore, the invention provides pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.