Neutralizing monoclonal antibody specific for rodent human interleukin - 18, a neutralizing Fab fragment or fragment F (AB ') 2A region of light chain complementarity inmonoglobulina (COR), a Molecule of nucleic acid, Pharmaceutical composition containing same.

摘要

Chimeric, humanized and other IL-18 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.