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A process for purifying lovastatin and simvastatin with reduced levels of dimeric impurities.
A process for purifying lovastatin and simvastatin with reduced levels of dimeric impurities.
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机译:一种具有降低的二聚体杂质含量的洛伐他汀和辛伐他汀的纯化方法。
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摘要
A process reducing the levels of dimeric impurities in a statin to less than 0.08% by treatment of a statin containing more than 0.08% dimeric impurities with a mild base in a suitable solvent mixture.
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