18BETA, 19 BETA-DIACETYLOXY-18ALPHA-19ALPHA-EPOXY-3.13 (16) 14 CLERODATRIEN-2-ONE (ESCULENTIN A) ET 18BETA, 19BETA-DIACETYLOXY-18ALPHA-19ALPHA-EPOXY- 3, 12, 14ATR 2BETA-ISOVALERYLOXY-16BETA-7ALP A-DIOL (ESCULENTIN B). METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR THE PROVISION OF MEDICINAL PRODUCTS

摘要

The invention relates to the compounds 18 beta , 19 beta -diacetyloxy-18 alpha , 19 alpha -epoxy-3, 13(16), 14-clerodatrien-2-one (Esculentin A) and 18 beta , 19 beta -diacetyloxy-18 alpha , 19 alpha -epoxy-3, 12, 14-clerodatrien-2 beta -isovaleryloxy-6 beta , 7 alpha -diol (Esculentin B) obtained from plants belonging to the Samydaceae family, particularly Casearia esculenta, a process for their preparation, and their use in the manufacture of medicaments. The compounds are particularly useful as anti-inflammatory and/or anti-cancer agents.