Halogenated calixpyrroles, calixpyridinopyrroles and calixpyridines, and uses thereof

摘要

The present invention provides halogenated calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles having 4-12 pyrrolic rings with greater stability, enhanced anion and neutral molecule binding affinity, and different binding selectivites as compared to their non-halogenated congeners as judged from SUP1/SUPH NMR, SUP19/SUPF NMR and fluorescence emission spectroscopic analyses.