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NOVEL PROTEINS BINDING TO MAMMALIAN TARGET OF RAPAMYCIN (mTOR) AND GENES THEREOF

机译:新蛋白结合雷帕霉素(mTOR)的哺乳动物目标及其基因

摘要

It is intended to provide novel proteins binding to mammalian target of rapamycin (mTOR) and genes thereof. Namely, genes encoding any of the following proteins (a) to (c). (a) A protein comprising an amino acid sequence represented by SEQ ID NO:2 or 4. (b) A protein comprising an amino acid sequence derived from an amino acid sequence represented by SEQ ID NO:2 or 4 by substitution, deletion, insertion and/or addition of one or more amino acids and binding to mammalian target of rapamycin (mTOR). (c) A protein comprising an amino acid sequence derived from an amino acid sequence represented by SEQ ID NO:2 or 4 by substitution, deletion, insertion and/or addition of one or more amino acids and binding to a protein having a TOS motif (mTOR signaling motif).
机译:目的是提供与哺乳动物雷帕霉素靶标(mTOR)结合的新型蛋白质及其基因。即,编码以下蛋白质(a)至(c)中的任何一种的基因。 (a)包含由SEQ ID NO:2或4表示的氨基酸序列的蛋白质。(b)包含通过取代,缺失,插入和/或添加一种或多种氨基酸,并与雷帕霉素(mTOR)的哺乳动物靶标结合。 (c)一种蛋白质,其包含通过取代,缺失,插入和/或添加一个或多个氨基酸并结合具有TOS基序的蛋白质而衍生自SEQ ID NO:2或4表示的氨基酸序列的氨基酸序列。 (mTOR信号基序)。

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