首页> 外国专利> Product comprising rapamycin or particular derivatives and an NMDA or AMPA antagonist for use for the treatment of epilepsy or Huntington's Disease, and the use of rapamycin or particular derivatives for the manufacture of a medicament for the treatment of epilepsy or Huntington's Disease.

Product comprising rapamycin or particular derivatives and an NMDA or AMPA antagonist for use for the treatment of epilepsy or Huntington's Disease, and the use of rapamycin or particular derivatives for the manufacture of a medicament for the treatment of epilepsy or Huntington's Disease.

机译:包含雷帕霉素或特定衍生物和NMDA或AMPA拮抗剂的产品,用于治疗癫痫或亨廷顿氏病,以及雷帕霉素或特定衍生物在制备用于治疗癫痫或亨廷顿氏病的药物中的用途。

摘要

This invention provides a method of using rapamycin, rapamycin 1,3-Diels Alder adduct with phenyltriazolinedione, rapamycin 42-ester with 4-ÄÄ4-(dimethylamino)phenylÜazoÜbenzenesulfonic acid, rapamycin 1,3-Diels Alder adduct with methyltriazolinedione, or rapamycin-O-benzyl-27-oxime as a neuroprotective agent.
机译:本发明提供了使用雷帕霉素,雷帕霉素1,3-Diels Alder与苯基三唑啉二酮加合物,雷帕霉素42-酯与4-Ä4-4-二甲基氨基苯基偶氮苯磺酸,雷帕霉素1,3-Diels Alder与甲基三唑啉二酮或雷帕霉素-O加合物的方法。 -苄基-27-肟作为神经保护剂。

著录项

  • 公开/公告号EP0778023B1

    专利类型

  • 公开/公告日2003-03-12

    原文格式PDF

  • 申请/专利权人 WYETH;

    申请/专利号EP19960308786

  • 申请日1996-12-04

  • 分类号A61K31/445;A61P25/08;A61P25/14;

  • 国家 EP

  • 入库时间 2022-08-21 23:54:17

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