new topical compositions that melatonin or its analog in very low doses, and their use in cosmetics

摘要

Topical compositions contain melatonin (MT) or one of its analogues (I) in a cosmetic or pharmaceutical carrier. The novelty is that the amount of MT or (I) present is (i) sufficient to allow, after topical application, the passage into the skin of 10-15 - 10-7M of MT or (I) or (ii) below 10-4 wt.%.