GENETIC DIAGNOSIS OF HYPERTENSION OR HYPOTENSION UTILIZING POLYMORPHISM IN MATRIX METALLOPROTEINASE 9 GENE AND NUCLEIC ACID MOLECULE USED THEREFOR

摘要

PROBLEM TO BE SOLVED: To provide a method for genetic diagnosis of hypertension or hypotension in females.;SOLUTION: A codon encoding alanine in Ala20Val polymorphism in a matrix metalloproteinase 9 gene is used as a risk factor for the hypertension in the females. Furthermore, a T allele in C(-1562) T polymorphism and a codon encoding glutamine in Arg668Gln polymorphism are used as the risk factor for the hypotension in the females.;COPYRIGHT: (C)2005,JPO&NCIPI