首页> 外国专利> A novel aminopeptidase derived from Bacillus licheniformis, a gene encoding the aminopeptidase, an expression vector containing the gene, a transformant using the expression vector, and a method for producing a natural protein using the expression vector

A novel aminopeptidase derived from Bacillus licheniformis, a gene encoding the aminopeptidase, an expression vector containing the gene, a transformant using the expression vector, and a method for producing a natural protein using the expression vector

机译:一种来自地衣芽孢杆菌的新型氨肽酶,编码该氨肽酶的基因,包含该基因的表达载体,使用该表达载体的转化体以及使用该表达载体生产天然蛋白质的方法

摘要

The present invention relates to novel aminopeptidase derived from Bacillus licheniformis, a gene encoding the aminopeptidase, an expression vector containing the gene, a cell transformant transfected with the expression vector and a process for preparing a natural type protein using thereof. More particularly, the present invention relates to a gene encoding aminopeptidase which is cloned and manufactured using the recombinant DNA technique, an expression vector containing the gene, a cell transformant transfected with the expression vector and a recombinant aminopeptidase which is necessary to produce recombinant human growth hormone in a natural type protein and can be expressed in a high yield more stably and advantageously, compared with conventional methods for the purification.
机译:本发明涉及衍生自地衣芽孢杆菌的新型氨基肽酶,编码该氨基肽酶的基因,包含该基因的表达载体,用该表达载体转染的细胞转化体以及使用其制备天然型蛋白质的方法。更具体地,本发明涉及使用重组DNA技术克隆和制备的编码氨肽酶的基因,包含该基因的表达载体,用该表达载体转染的细胞转化体和重组人肽,其是产生重组人生长所必需的。与常规的纯化方法相比,它可以更稳定,更有利地以高产率表达天然型蛋白质中的激素。

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