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Pharmaceutical composition for treatment of secondary hyperparathyroidism and therapeutic agent for cardiovascular complications associated with treatment of secondary hyperparathyroidism

机译:用于治疗继发性甲状旁腺功能亢进的药物组合物和用于治疗继发性甲状旁腺功能亢进相关的心血管并发症的治疗剂

摘要

An object of the present invention is to provide a pharmaceutical composition for treating secondary hyperparathyroidism that can reduce the induction of cardiovascular complications due to calcification, and to provide a secondary composition in dialysis patients. An object of the present invention is to provide a therapeutic or preventive agent for cardiovascular complications (eg, arteriosclerosis, ischemic heart disease, etc.) due to calcification accompanying the treatment of hyperthyroidism. According to the present invention, a pharmaceutical composition for treating secondary hyperparathyroidism, comprising, as an active ingredient, a vitamin D derivative having no action of inducing cardiovascular complications due to calcification, and 1α, Secondary hyperparathyroidism in dialysis patients containing 3β-dihydroxy-20S- (3-hydroxy-3-methylbutyloxy) -9,10-seco-5,7,10 (19) -pregnatriene as an active ingredient The present invention provides a therapeutic agent for cardiovascular complications due to calcification associated with the treatment of sickness.
机译:本发明的目的是提供一种用于治疗继发性甲状旁腺功能亢进的药物组合物,其可以减少由于钙化引起的心血管并发症的诱导,并且提供用于透析患者的继发组合物。本发明的目的是提供用于治疗伴随甲状腺功能亢进症的钙化引起的心血管并发症(例如,动脉硬化,缺血性心脏病等)的治疗剂或预防剂。根据本发明,一种用于治疗继发性甲状旁腺功能亢进的药物组合物,其包含作为活性成分的,不引起因钙化引起的心血管并发症的作用的维生素D衍生物和包含3β-二羟基-20S的透析患者中​​的1α继发性甲状旁腺功能亢进。 -(3-羟基-3-甲基丁氧基)-9,10-seco-5,7,10(19)-孕三烯作为活性成分本发明提供了用于治疗与疾病相关的钙化引起的心血管并发症的治疗剂。 。

著录项

  • 公开/公告号JPWO2003004036A1

    专利类型

  • 公开/公告日2004-10-21

    原文格式PDF

  • 申请/专利权人 中外製薬株式会社;

    申请/专利号JP20030510047

  • 发明设计人 平田 道則;

    申请日2002-07-02

  • 分类号A61K31/59;A61P5/18;A61P9/10;

  • 国家 JP

  • 入库时间 2022-08-21 23:25:49

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