Method of measuring the antibody specific autoimmune disease diagnostic methods, nucleosome DNA production method, DNA plate, DNA plate production process, as well as anti-DNA antibody measurement method of manufacturing the same, nucleosomes and mononucleosomes

摘要

Efficiently, moreover, to provide a method for producing mono-nucleosome can be produced in high purity and easily mononucleosomes. Capture and collection process to capture collected by the antibody specific for the nucleosome, the nucleosome that is included in the sample, Dissociation and recovery process of dissociating the antibody recovered from the nucleosomes captured, The isolation and purification process of isolation and purification based on molecular weight mono-nucleosome from nucleosomes was collected, It is a process for the manufacture of mononucleosomes containing the.