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Interaction test for the investigation of inhibitory molecules of the interaction between a presenilin and the amp;bgr;-amyloid peptide
Interaction test for the investigation of inhibitory molecules of the interaction between a presenilin and the amp;bgr;-amyloid peptide
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机译:相互作用试验,用于研究早老素与β淀粉样肽之间相互作用的抑制分子
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摘要
Provided herein are novel peptide and nucleotide sequences, their pharmaceutical use, as well as novel polypeptides capable of inhibiting at least partially the interaction between presenilin 1 or presenilin 2 and the &bgr;-amyloid peptide precursor or a &bgr;-amyloid peptide; also provided are in vitro tests and methods for detecting molecules and in particular, molecules capable of inhibiting said interaction.
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