Apparatus for the formation of partu00ecculas micronized and submicronizadas of a substance.Nozzle for introducing a solution of a substance and a fluid supercru00ectico in a vessel of partu00ecculas formation, and.Process for the formation of partu00ecculas micronized and submicronizadas a substance

摘要

"Apparatus for formation of partu00ecculas micronized and submicronizadas of a substance.Nozzle for introducing a solution of a substance and a fluid supercru00ectico in a vessel of partu00ecculas formation, and.Process for the formation of partu00ecculas micronized and submicronizadas a substance ".It is described an apparatus for formation of micronized particles of a substance and submicronizadas using the process gas.Comprising a vessel of particle formation (22) and means for introducing a solution of the substance and a supercritical fluid into a formation of particles (22).Where such means comprise a nozzle (27) having a central hole (39) that serves to carry a flow of solution.And several outer holes separated (41) which serve to carry a flow of supercritical fluid pure or a flow of supercritical fluid mixed with a modifier.So that the solvent is extracted from the solution by supercritical fluid occurring precipitation of micronized particles and submicronizadas.It is also described a process performed with this apparatus.