A compound, pharmaceutical composition, and methods for inhibiting the activity of dipeptidyl peptidase iv in a mammal for the treatment, control, or prevention of diabetes, hyperglycemia, obesity, insulin resistance, one or more disorders, atherosclerosis, of one or more conditions, for the treatment or control of growth hormone deficiency and hiv infection, for modulating the immune response and for reducing sperm motility

摘要

"COMPOSITION, PHARMACEUTICAL COMPOSITION, AND METHODS FOR INHIBITING THE ACTIVITY OF THE DIPEPTIDIL-PEPTIDASE IV ENZYME IN A MAMMER, FOR TREATMENT, CONTROL, OR PREVENTION OF DIABETES, HYPERGLYCEMIA, INSIS, DISEASE, RESISTANCE, DIFFERENCE, ATHEROSCLEROSIS OF ONE OR MORE CONDITIONS FOR TREATMENT OR CONTROL OF GROWTH AND HIV INFECTION HORMONE DEFICIENCY, FOR MODULATION OF IMMUNE RESPONSE AND REDUCTION OF SPERM MOBILITY ". The present invention relates to compounds which are dipeptidyl peptidase-IV enzyme inhibitors ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.