Mycoplasma bovis infection model and methods for administration of m. bovis and for the induction of pneumonic lung lesions

摘要

"MODEL OF MYCOPLASMA BOVIS INFECTION AND METHODS FOR ADMINISTRATION OF M. BOVIS AND FOR INDUCTION OF LUNG PNEUMATIC INJURIES". The present invention provides a reproducible experimental model of M. bovis infection and methods for reliably inducing and establishing a disease or disorder caused by M. bovis infection by administering to an animal an effective amount. from a M. bovis culture. The experimental infection culture of the present invention is administered in an amount sufficient to induce humoral or cellular specific immune responses. The experimental M. bovis infection model according to the present invention can be used to evaluate the efficacy of potential vaccines.