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Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
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机译:奥氮平水合物的制备方法及其转化为奥氮平的结晶形式
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摘要
The present invention relates to a method for the preparation of hydrates of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno [2,3-b] [1,5] benzodiazepine (hereinafter referred to as Olanzapine). The present invention also relates to a process for conversion of these hydrates into a pure crystalline form of olanzapine referred to as form-I. The present invention also relates to a method of converting Olanzapine Form-2 to Form-1.
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