METHOD FOR PREDICTING DEVELOPMENT OF PRE-ECLAMPSIAMETHOD FOR PREDICTING DEVELOPMENT OF PRE-ECLAMPSIA IN PREGNANT WOMEN WITH PRIMARY ARTERIAL HYPERTENS IN PREGNANT WOMEN WITH PRIMARY ARTERIAL HYPERTENSION ION

摘要

The method for predicting the development of pre-eclampsia in pregnant women with the primary arterial hypertension comprises the assessment of the immunologic parameters within 20 weeks of gestation. In particular, several cytokines are assayed: interleukin-2, tumor necrosis factor alpha, and interleukin-10. In addition, the natural killers are counted. The increase in interleukin-2 level over 30 pg/ml, the increase in tumor necrosis factor alpha content up to 50.5 pg/ml and above, the decrease in interleukin-10 level below 12.0 pg/ml, and 15% increase in natural killer count are regarded as the prognostic features suggesting the development of pre-eclampsia in the early stages of gestation.