PHARMACEUTICAL COMPOSITION FOR CONTROLLED RELEASE OF BONE GROWTH PROMOTING COMPOUND, METHOD FOR OBTAINING IMPLANT FOR DELIVERY OF BONE GROWTH PROMOTING COMPOUND

摘要

The present invention is directed to an improved system for controlled release of a bone growth promoting compound and to a flowable composition for its formation. The flowable composition is composed of a bone growth promoting compound, a thermoplastic polymer and an organic solvent. The flowable composition is capable of forming a biodegradable and/or bioerodible microporous, solid polymer matrix. The matrix is useful as an implant in patients (humans and animals) for delivery of a bone growth promoting compound to certain tissues.