Ribavirin® is administered to a patient in a dosage range which is effective to modulate lymphokine expression in activated T cells. In particular, Ribavirin® is used to suppress Th2-mediated T cell responses and promote Th1-mediated T cell response. In other apsects of the invention, one or more Ribavirin® analogs are administered to a patient in a dosage range which is effective to modulate lymphokine expression in activated T cells. The Ribavirin® analog(s) may be used to suppress or enhance Th1 or Th2-mediated T cell responses.
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