GLYCOSILATED CATIONIC LIPIDS FOR LIPOSOMES USED IN DRUG DELIVERY

摘要

A nucleic acid delivery complex is provided which comprises a condensed polypeptide/nucleic acid complex and a cationic lipid wherein the complex comprises (a) a nucleic acid sequence of interest (NOI); and (b) at least pV adenoviral nucleic acid packaging polypeptides, or derivatives thereof, said polypeptides or derivatives thereof being (i) capable of binding to the NOI; and (ii) capable of condensing the NOI; and wherein the NOI is heterologous to the polypeptide. Also provided is a method in introducing an NOI into a cell using the delivery vector. IMAGE