PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING TH1 AND TH2 CELL RELATED DISEASES BY MODULATING THE TH1/TH2 RATIO.

摘要

Pharmaceutical composition for preventing or treating a Th1 cell- or Th2-cell-related disease in a human or an animal by modulating the Th1/Th2 ratio comprising an active substance consisting of (i) IL-4 and SDF-1 alpha , or IL-2 and SDF-1 alpha , respectively, as well as modulators thereof, (ii) an IL-4 stimulating adjuvant and SDF-1 alpha , or an IL-2 stimulating adjuvant and SDF-1 alpha , respectively, (iii) a modulator of the tyrosine kinases Syk or ZAP-70, or (iv) a modulator of the nuclear factors of activated T cells NFAT1 or NFAT2.