Cloning, expression and characterization of the total sequence of phosphodiesterase 8b

摘要

A nucleic acid which codes for human pde8b, dollars a (a) - a dna sequence according to fig.). 10, Dollar a (b) a different sequence, which, however, for the same amino acid sequence encoded, dollars a (c) a sequence that, for a protein with mutations or deletions, which the activity are not substantially changed, or dollars a (d) a with the sequence according to fig.). 10 hybridizing sequence, as long as they are for a protein with pde8b - activity coded. Dollars a is an expression vector according to the invention contains such a sequence is inserted into a suitable vector.