Diagnosis, prognosis and monitoring of cardiac disease, useful e.g. for selecting therapy, by determining the serum concentration of soluble CD40 ligand, a specific marker for platelet activation

摘要

Analysis of samples associated with cardiovascular diseases comprises: (i) incubating the sample with one or more molecules (A) that bind specifically to soluble CD40 ligand (sCD40L); (ii) detecting and/or quantifying sCD40L by an immunological method; and (iii) comparing the result with a reference value or with results from a reference sample. An Independent claim is also included for a diagnostic kit containing materials for performing the new method, optionally also other components and/or auxiliaries.