MOLDING OBTAINED FROM FISH-DERIVED COLLAGEN AND ITS THERMAL DENATURATION MATERIAL

摘要

PROBLEM TO BE SOLVED: To provide a hemostatic material which has both of sufficient stability and hemostatic property, having less risk of a pathogen which mammal-derived collagen or gelatin latently has by using a fish-derived collagen without using a crosslinking agent.;SOLUTION: This molding is obtained by crosslinking mixture of the fish-derived collagen with its thermal denaturation material by a method without using any crosslinking agent, has solubility to phosphate buffer saline of 37°C neither containing calcium ion nor magnesium ion, of 70% or less, has the favorable hemostatic property and an appropriate in-vivo stability and can be favorably used for the hemostatic material.;COPYRIGHT: (C)2005,JPO&NCIPI