TOPICAL VASORUM DELIVERING OF ETOPOSIDE IN COMBINATION WITH RAPAMYCIN FOR PREVENTING RESTINOSIS AFTER TRAUMA OF VASORUM

摘要

PPROBLEM TO BE SOLVED: To provide a medical device which can be coated to minimize or substantially eliminate certain biological reaction against the introduction of the medical device into a living body, especially a medical device which can be implanted. PSOLUTION: The certain living body reaction against the introduction of the medical treatment device into a living body is reduced by mixing various kinds of medicines, drugs or formulations for treatment with biocompatible materials to secure them to at least a part of medical treatment device. The medicines, drugs or formulations for treatment promotes healing including the formation of the coagulation of blood, and promotes endothelialization. The device used for delivering the implantable medical device reduces possibility to damage the implantable medical device during arrangement. These medical treatment devices include stents, grafts, anastomosing devices, circumvascular wraps, sutures, and staples. Further, the products combined with the various kinds of polymers control or regulate the dissolving speed of the medicines, drugs or formulations for treatment. PCOPYRIGHT: (C)2006,JPO&NCIPI