Method for using saddle-point approximation for the evaluation of intractable conditional probabilities in biotechnology

摘要

A method and system for determining a probability of observing false matches between spectral peaks of an unknown source and spectral peaks of known microorganisms are provided. The method and system include using the saddle-point approximation to determine the probability of observing false matches between the spectral peaks of the unknown source and the spectral peaks of the known microorganisms. The method and system further include testing the null hypothesis to determine whether the unknown source is a known microorganism.