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Type II thioesterase from streptomyces coelicolor a3(2) and the coding sequence
Type II thioesterase from streptomyces coelicolor a3(2) and the coding sequence
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机译:链霉菌a3(2)的II型硫酯酶及其编码序列
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摘要
The invention concerns a biosynthesis of nonaramatic polyketide compounds. More particularly, the present invention relates to a isolated polynucleotide molecule, a nucleic acid vector comprising the molecule, and isolated polypeptide and uses thereof. A new, type II thioestrerase can be obtained as an application outcome of this invention. The enzyme is active in polyketide, especially macrolide, biosynthesis when associated with a multienzyme complex of a polyketide synthase. The activity of the enzyme results in a increase of polyketide biosynthesis efficiency.
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