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Synthesis of chiral furan amino acids as novel peptide building blocks
Synthesis of chiral furan amino acids as novel peptide building blocks
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机译:合成手性呋喃氨基酸作为新型肽基
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摘要
The present invention provides a chiral furan amino acids, in enantiomerically pure forms, either R or S. The starting materials are being used chiral N-terminal-protected amino aldehydes derived from the corresponding N-terminal-protected protected L- or D-amino acids. The present invention also relates to a process for preparing these chirally substituted furan amino acids constitute an important class of conformationally constrained peptide based molecules that can be used as dipeptide isosteres in peptidomimetic studies.
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