Oral dosage form comprising 5 - 4 - 2 - (n-methyl-n - (2-pyridyl) amino) ethoxy benzyl - - - - - tiazolidino 2,4 Dione and other additional Antidiabetic agent; Process for their Preparation and use of 5 - 4 - 2 - (methyl - N - (2-pyridyl) amino) ethoxy benzyl - - - - - tiazolidino 2,4 Dione and another Antidiabetic Agent

摘要

An oral dosage form comprising an erodible Core which includes 5 - [4 - [2 - (n-methyl-n - (2-pyridyl) amino) ethoxy] benzyl] - - - - - tiazolidino 2,4 Dione compounds (a), or a pharmaceutically acceptable Salt or solvate of the same, and another additional Antidiabetic Agent, in which the core Tien And a Coating with one or Multiple Openings which lead to the kernel.Where the coating erodes under Predetermined pH conditions.Procedure for the preparation of the oral dosage form comprising: (a) Prepare an erodible Core tablet, which comprises the compound or a pharmaceutically acceptable Salt or solvate thereof,Additional and another Antidiabetic agent; b) coating the core material is eroded in a pH dependent manner; and (c) create one or multiple holes in the coating.Use of 5 - [4 - [2 - (n-methyl-n - (2-pyridyl) amino) ethoxy] benzyl] - - - - - tiazolidino 2,4 Dione, or a pharmaceutically acceptable Salt or solvate of the same, and another Antidiabetic Agent to prepare an oral dosage form for the treatment prophylaxis and / or diabetes mellitus, among othersWhich comprises administering to said Mammal oral dosage form to a human or non-human as required.