Method for improving specifically and selectively the expression of gene mRNA of collagen type II in cartilage tissue, the device, and methods of treatment of at least one of osteoarthritis.Rheumatoid arthritis, cartilage lesion and imperfections.

摘要

Method for improving specifically and selectively the expression of gene mRNA of collagen type II in cartilage tissue, the device, and methods of treatment of at least one of osteoarthritis.Rheumatoid arthritis, injury and imperfections of the cartilage.Methods and devices for regulating gene expression of collagen type II in cartilage cells via the application of fields generated by specific and selective electrical signals.And electromagnetic specific and selective in the treatment of articular cartilage ill or injured.By means of gene expression is regulated to increase or decrease the process by which specific parts (genes) of the human genome (DNA) are transcribed into mRNA and, later,Processed in protein.Are methods and devices for the treatment of cartilage tissue of injured or ill.That includes generating electrical signals and electromagnetic specific and selective and electromagnetic signals which generate fields optimized for specific and selective expression of type I collagen gene.I and expose the cartilage tissue to the fields generated by specific and selective, specific and selective signals to regulate gene expression of collagen type II in cartilage tissue.The methods and devices resulting from is useful for the treatment of osteoarthritis, rheumatoid arthritis, injury of cartilage and cartilage defects target.