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An Improved Process for preparation of Rofecoxib
An Improved Process for preparation of Rofecoxib
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机译:罗非考昔的改进制备方法
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摘要
An improved process of the preparation of Rofecoxib of the Formula 1 is disclosed. The process cimprises cyclizing an ester of Formula 3 in the presence of a suitable aprotic polar solvent, an organic base and a phase transfer catalyst.
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