Powder formulation containing antagonist CGRP (1 - N2 - (3,5 - Bromine - N - ((4 - (3,4-dihydro - 2 (1H) - oxoquinazolin - 3 - yl) - piperidinyl) - carbonyl) - D - L lysyl tyrosyl) - 4 - (4) - - piridinil) - piperazine, Process for their Preparation and their use as inhaled

摘要

The invention is reduced to a lung or nasal aspirated powder, which includes a surface particle in the form of CGRP 1 - (N2 - (3,5-dibromo-n - ((4 - (3,4-dibromo-n -) (4 - (3,4-dibromo-n -) (oxoquinazolin-3-il) - 1-piperidinil) - carbonil - (d-thyroid) - L-lysine) - 4 - (4-pyridine) - piperazina (a), SC (50t) under standard conditions, Relative humidity 75%,The inanimate state of these particles, the preparation procedure, and the procedure used to make inhaled powder for headache treatment, migrators, and cluster headaches remain stable.