Intranasal delivery of pneumococcal polysaccharide vaccines

摘要

The invention relates to a method for preventing against diseases induced by Streptococcus pneumoniae infections, which comprises mucosally administering to a patient in need a S. pneumoniae capsular polysaccharide. This latter may be conjugated or not and is preferably mixed with a mucosal adjuvant such as cholera toxin, E. coli heat-labile toxin or Rhinovax TM . A preferred route of administration is the intranasal route.