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USE OF ULTRAVIOLET, NEAR-ULTRAVIOLET AND NEAR INFRARED RESONANCE RAMAN SPECTROSCOPY AND FLUORESCENCE SPECTROSCOPY FOR TISSUE INTERROGATION OF SHOCK STATES, CRITICAL ILLNESSES, AND OTHER DISEASE STATES
USE OF ULTRAVIOLET, NEAR-ULTRAVIOLET AND NEAR INFRARED RESONANCE RAMAN SPECTROSCOPY AND FLUORESCENCE SPECTROSCOPY FOR TISSUE INTERROGATION OF SHOCK STATES, CRITICAL ILLNESSES, AND OTHER DISEASE STATES
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机译:紫外线,近端和近红外拉曼光谱和荧光光谱在组织状态,病态,严重疾病和其他疾病的研究中的应用
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摘要
In an emergency medicine patient, accurate measurement of change or lack thereof from non-shock, non-ischemic, non-inflammation, non-tissue injury, non-immune dysfunction conditions is important and is provided, as practical, real-time approaches for accurately characterizing a patient's condition, using Raman (3) and/or fluorescence (30) spectroscopy with a high degree of accuracy. Measurement times are on the order of seconds. High-accuracy measurement is achieved with Raman spectroscopy interrogation of tissue. Simultaneous interrogation by NADH fluorescence spectroscopy may be used. Measurements may be non-invasive to minimally invasive. Preclinical (ultra-early) states of shock can be detected (5), severity can be determined, and the effectiveness of various treatments can be determined.
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