LIQUID PREPARATION CONTAINING IMMUNOGLOBULIN EFFICIENT AGAINST MARBURG FEVER FROM HORSE BLOOD SERUM (HORSE IMMUNOGLOBULIN MARBURG)

摘要

FIELD: clinical immunology.;SUBSTANCE: preparation represents 9.0-11.0% solution of horse blood serum immunoglobulins with pH 7.0-7.5 and content of γ-immunoglobulin fraction at least 90.0% of the total protein. Nonspecific fractions in preparation are albumin, α- and β-globulin fractions in amount not larger than 10.0%, and residual ethyl alcohol in amount not larger than 4.0%. Preparation is characterized by virus-neutralizing antibodies against virus Marburg. Titer of virus-neutralizing antibodies is at least 1:2048 and can be used for emergency prevention of Marburg fever in humans.;EFFECT: extended immunoglobulin application area.;1 tbl