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A process for the investigation of an active ingredient influence on biological cells

机译:研究活性成分对生物细胞影响的方法

摘要

In the case of a process for the investigation of the active substance effect on cells, these are on a sample carrier (13, 14) immobilized, the in a reaction chamber (12) is accommodated. By the action of the reaction chamber with the active substance (for example, in the nutrient solution for the cells contain) can be electrical signals via the electrically conductive sample carrier (14) is read out, the a conclusion on the electrical properties of the cells (11) permit. In this way, especially a dying of the cells to be determined, as a result of which the toxic effect of the active ingredient can be investigated. As a result of this examination, the otherwise necessary tests on animals limited or even be dispensed with (customary ld50 - toxicity).
机译:在研究活性物质对细胞的作用的方法的情况下,这些物质在固定的样品载体(13、14)上,并容纳在反应室(12)中。通过反应室与活性物质(例如在细胞中所含的营养液中)的作用,可以通过导电的样品载体(14)读出电信号,得出有关电性能的结论。单元格(11)允许。以这种方式,尤其是待确定细胞的死亡,其结果是可以研究活性成分的毒性作用。这种检查的结果是,对动物的其他必要测试受到限制,甚至省去了(习惯的ld50-毒性)。

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