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New of chiral salen 2 - catalyst and method for the production of chiral compounds from racemic epoxides with the use of the novel catalyst

机译:手性Salen 2的新型催化剂和利用外消旋环氧化物制备手性化合物的方法。

摘要

There are provided new chiral salen catalyst, and methods for the preparation of chiral compounds from racemic epoxides by using new catalyst. More particularly, there are provided new chiral compounds from racemic epoxides by using new catalyst. More particularly, there are provided new chiral salen catalyst which has new molecular structure, which can be recycled without any additional regeneration process because the catalyst retains its catalystic activity even after the repeated use, and which causes no or little racemization which results from the reverse reaction of the produced chiral compound, and methods for the mass production of chiral compounds, which is usefuld as an intermediate for the manufacture of drugs and food additives, from racemic epoxides by using the catalyst in an economic manner and with high optical purity.
机译:提供了新的手性salen催化剂,以及通过使用新的催化剂由外消旋环氧化物制备手性化合物的方法。更特别地,通过使用新的催化剂,由外消旋环氧化物提供了新的手性化合物。更特别地,提供了具有新的分子结构的新的手性塞林催化剂,其可以被循环使用而无需任何额外的再生过程,因为该催化剂即使在重复使用之后仍保持其催化活性,并且不会或几乎不会引起由反向产生的外消旋化。通过以经济的方式和高光学纯度使用该催化剂,由外消旋环氧化物用作所生产的手性化合物的反应和大量生产手性化合物的方法,该方法可用作外消旋环氧化物生产药物和食品添加剂的中间体。

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