首页> 外国专利> New neuroactive 6-alkanoyl-4,5-dialkyl-1,10-epoxy-7-alkanoyloxy-decahydro-2-naphthols, useful as e.g. insecticides or antiparkinsonian drugs, are calcium channel activators

New neuroactive 6-alkanoyl-4,5-dialkyl-1,10-epoxy-7-alkanoyloxy-decahydro-2-naphthols, useful as e.g. insecticides or antiparkinsonian drugs, are calcium channel activators

机译:新的神经活性的6-烷酰基-4,5-二烷基-1,10-环氧-7-烷酰氧基-十氢-2-萘酚,例如杀虫剂或抗帕金森病药物是钙通道激活剂

摘要

6-Alkanoyl-4,5-dialkyl-1,10-epoxy-7-alkanoyloxy-decahydro-2-naphthols (A) are new. 6-Alkanoyl-4,5-dialkyl-1,10-epoxy-7-alkanoyloxy-decahydro-2-naphthols of formula (A) are new. [Image] R 1-R 4methyl or ethyl. ACTIVITY : Insecticide; Antiparkinsonian. 6S-Acetyl-4R,5R-dimethyl-1R,10S-epoxy-7R-acetoxy-decahydro-2R-naphthol had a minimum active concentration of 3.1 Microg/Microl per 10 larvae against Phormia terrae novaelarvae when injected into the last abdominal segment of the larvae as a solution in water/dimethyl sulfoxide. MECHANISM OF ACTION : Calcium channel activator; Dopaminergic.
机译:6-烷酰基-4,5-二烷基-1,10-环氧-7-烷酰氧基-十氢-2-萘酚(A)是新的。式(A)的6-链烷酰基-4,5-二烷基-1,10-环氧-7-烷酰氧基-十氢-2-萘是新的。 [图像] R 1 -R 4甲基或乙基。活性:杀虫剂;反帕金森人。当将6S-乙酰基-4R,5R-二甲基-1R,10S-环氧-7R-乙酰氧基-十氢-2R-萘酚注射到甲壳虫的新腹部时,其最小活性浓度为每10幼虫3.1微克/微升。幼虫在水/二甲亚砜中的溶液。作用机理:钙通道激活剂;多巴胺能。

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