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Catanionic membrane useful as a carrier for drugs or volatile molecules comprises a bilayer of anionic and cationic surfactants stabilized with a polymer
Catanionic membrane useful as a carrier for drugs or volatile molecules comprises a bilayer of anionic and cationic surfactants stabilized with a polymer
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机译:用作药物或挥发性分子载体的阳离子膜包含一层用聚合物稳定的阴离子和阳离子表面活性剂双层
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摘要
Catanionic membrane in the form of an organized solid bilayer comprising a lateral alternation of cocrystallized anionic surfactants with hydrogen counterions and cationic surfactants with hydroxyl counterions is stabilized by adsorption of a polymer that is partially hydrophobic or has an overall negative charge. The anionic/cationic surfactant molar ratio is greater than 1. An independent claim is also included for for producing a catanionic membrane as above by mixing the molten anionic and cationic surfactants in a low-conductivity aqueous solvent to form unilamellar vesicles, cooling the mixture to form flat aggregates comprising a single crystallized molecular bilayer, and stabilizing the bilayers by adding a solution of the polymer in a low-conductivity aqueous solvent. For x moles of cationic surfactant, there are x moles of anionic surfactant with a hydrogen counterion and less than 2x moles of anionic surfactant with a hydrogen or metal counterion.
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