首页> 外国专利> Compound 1- N2- 3,5-dibromo-N-4- (3,4-dihydro-2 (1H) -oxoquinazolin-3-yl) -1-piperidinyl for the treatment of migraine -Carbonyl -D-tyrosyl -L-lysyl -4- (4-pyridinyl) -piperazine hydrochloride in combination with sumatriptan

Compound 1- N2- 3,5-dibromo-N-4- (3,4-dihydro-2 (1H) -oxoquinazolin-3-yl) -1-piperidinyl for the treatment of migraine -Carbonyl -D-tyrosyl -L-lysyl -4- (4-pyridinyl) -piperazine hydrochloride in combination with sumatriptan

机译:化合物1- [N2- [3,5-二溴-N-[[4-(3,4-二氢-2(1H)-氧代喹唑啉-3-基)-1-哌啶基]用于治疗偏头痛-碳酰基] -D-酪氨酰基] -L-赖氨酰] -4-(4-吡啶基)-哌嗪盐酸盐与舒马普坦联用

摘要

The invention relates to a method for the treatment or prevention of headaches, migraines or cluster headaches, said method including the combined administration of a therapeutically active quantity of the hydrochloride of the active ingredient base 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine (A) and a therapeutically active quantity of the migraine active ingredient sumatriptan or a physiologically compatible salt thereof. The invention also relates to the corresponding pharmaceutical compositions and to the production of the same.
机译:本发明涉及一种用于治疗或预防头痛,偏头痛或丛集性头痛的方法,所述方法包括联合施用治疗有效量的活性成分碱1- [N 2-[3,5]的盐酸盐。 -二溴-N-[[4-(3,4-二氢-2(1H)-氧喹唑啉-3-基)-1-哌啶基]-羰基] -D-酪氨酰] -L-赖氨酰] -4-(4 -吡啶基)-哌嗪(A)和治疗有效量的偏头痛活性成分舒马曲坦或其生理相容性盐。本发明还涉及相应的药物组合物及其生产。

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