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PHARMACEUTICAL COMPOSITION AND MEDICAL TREATMENTS COMPRISING NOTCH LIGAND PROTEINS
PHARMACEUTICAL COMPOSITION AND MEDICAL TREATMENTS COMPRISING NOTCH LIGAND PROTEINS
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机译:含Notch配体蛋白的药物成分和药物治疗
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摘要
Provided is a Notch ligand protein or polypeptide comprising a Notch ligand DSL domain; 1 to 5 (but no more than 5) Notch ligand EGF repeat domains; optionally, all or part of a Notch ligand N-terminal domain; and optionally, one or more heterologous amino acid sequences. Also provided is a homogeneous or heterogeneous multimer of the protein or polypeptide and a polynucleotide encoding the Notch ligand protein or polypeptide. An immune response can be modified in a subject by administering the Notch ligand protein or polypeptide to the subject.
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