首页> 外国专利> Method for producing a microbial transglutaminase active from a pro transglutaminase microbial metaloprotease neutral actionomicetos, molecule of nucleic acid, and,Method for producing a metaloprotease neutral actinomicetos

Method for producing a microbial transglutaminase active from a pro transglutaminase microbial metaloprotease neutral actionomicetos, molecule of nucleic acid, and,Method for producing a metaloprotease neutral actinomicetos

机译:由转谷氨酰胺酶微生物金属蛋白酶中性作用基因组产生活性的微生物转谷氨酰胺酶的方法,核酸分子和制备金属蛋白酶中性作用基因组的方法

摘要

"Method for producing a microbial transglutaminase active from a pro transglutaminase microbial metaloprotease neutral actinomicetos, molecule of nucleic acid, and,Method for producing a metaloprotease neutral actinomicetos ".The present invention provides a metaloprotease neutral actinomicetos which selectively cleaves a part of Pro structure of a pro transglutaminase and a gene coding the same microbial.A microbial transglutaminase active of which part of Pro structure was excised can be produced by cultivating a microorganism having a gene encoding the neutral actinomice metaloproteaseIt described above introduced in it, allowing the microorganism to produce metaloprotease neutral actinomicetos and then treating the pro microbial transglutaminase with the same.
机译:“从转谷氨酰胺酶微生物金属蛋白酶中性放线菌素产生活性的微生物转谷氨酰胺酶的方法,核酸分子和产生金属蛋白酶中性放线菌素的方法。”本发明提供了选择性地裂解Pro的一部分的金属蛋白酶中性放线菌素。转谷氨酰胺酶的原结构和编码同一微生物的基因。通过培养具有上述中性编码放线菌属金属蛋白酶的基因的微生物,可以生产出一部分Pro结构被切除的微生物转谷氨酰胺酶活性。产生金属蛋白酶中性的actinomicetos,然后用同样的方法处理原微生物转谷氨酰胺酶。

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