complement inhibitory molecule, antibody, fusion protein, nucleic acid molecule, vector, host cell, methods for making a complement inhibitory molecule or its functional equivalent or fusion protein, to identify a ligand of a complement inhibitory molecule , or a functional equivalent thereof, to treat an animal suffering from a complement-mediated disease or disorder, or to prevent an animal from developing a complement-mediated disease or disorder, to vaccinate an animal against a transmitted disease or disorder. by a hematophagous arthropod and to inhibit classical and alternative complement pathways in a non-human cell, tissue or organism, composition, use of a complement inhibitory molecule, a fusion protein or a nucleic acid molecule

摘要

"COMPLEMENT INHIBITOR MOLECULE, ANTIBODY, FUSION PROTEIN, NUCLEIC ACID MOLECLE VECTOR HOST CELL, METHODS FOR PREPARING A COMPLEMENT INHIBITOR MOLLECLE OR A COMPUTERLY DIFFICULATED FOLLOWING A COMPUTERLY DIFFICULATED COMPLEMENTARY OR ITS FUNCTIONAL EQUIVALENT TO TREAT AN ANIMAL SUFFERED BY A DISEASE OR DISTURBUS MEDIATED BY THE COMPLEMENT, OR TO PREVENT AN ANIMAL DEVELOPING A DISEASE OR DISTURBUS MEDIATED BY THE COMPLEMENT OF A VACCIN A DIFFERENT TRANSACTION A HEMATOPHAGUS ARTHROPODE AND TO INHIBIT THE CLASSIC AND ALTERNATIVE COMPLEMENT ROUTE IN A NON-HUMAN CELL, TISSUE OR ORGANISM, COMPOSITION, USE OF A COMPLEMENT INHIBITOR MOLLECLE, A NUCLEUS FOLUS CELL PROTEIN OR The invention relates to complement inhibitors, which inhibit both the classical and alternative complement pathways. In particular, the invention relates to complement inhibitors derived from hematophagous arthropod salivary glands that inhibit both the classical and alternative complement pathways. The invention also relates to the use of such complement inhibitors in the treatment and prevention of diseases.