Aryl substituted piperazine derived Compounds, Pharmaceutical composition, Preparation method and its use in preparing medicine for treating Menopause, post Menopause,Peri Menopause, disorder of sleep.

摘要

The present Invention relates to Derivatives cicloalcanoilo aryl, substitutedThe compositions containing these derivatives and Methods of Use thereof for the Prevention and Treatment of conditions that improve the reuptake of monoamines, such asInter alia, vasomotor symptoms (SVM), sexual dysfunction, Gastrointestinal and Genitourinary disorders, Chronic Fatigue Syndrome, fibromyalgia Syndrome,Nervous System Disorders and combinations thereof, in particular those conditions selected from the group consisting of major depressive disorder.Vasomotor symptoms and urinary urgency incontinence, stress, fibromyalgia Pain, diabetic neuropathy, and combinations thereof.