A COMBINATION COMPRISING AN ENDOTHELIN RECEPTOR ANTAGONIST OR A PHARMACEUITCALLY ACCEPTABLE SALT THEREOF AND AN EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) TYROSINE KINASE INHIBITOR (TKI) OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMBINATIONS AND USE THEREOF IN THE MANUFACTURE OF MEDICAMENTS FOR THE TREATMENT OR PROPHYLAXIS OF CANCER

摘要

A combination, comprising an endothelin receptor antagonist, or a pharmaceutically acceptable salt thereof, and an EGFR TKI, or a pharmaceutically acceptable salt thereof is described.