ADENOVIRAL VECTORS FOR THE TRANSDUCTION OF CONDROCITS.

摘要

Use of a recombinant chimeric adenovirus of subgroup C as a vehicle to deliver a nucleic acid of interest to a primary human chondrocyte in vitro, wherein said adenovirus contains at least the knob domain of a fiber protein of an adenovirus selected from the group consisting of adenovirus serotype 8, 11, 16, 32, 35, 38, 40-S and 51.